Napoli’s hopes of winning Serie A for the first time since 1990 suffered a setback as a 3-0 rout at the hands of Fiorentina handed Juventus a clear advantage in the race for the title.
Defending champions Juve are four points clear with three games remaining.
Kalidou Koulibaly was sent off for kicking Giovanni Simeone, and the Argentinian struck thrice to lift La Viola to a first win in four games for mid-table Fiorentina.
Napoli played for 84 minutes with 10 men.
This season’s Serie A campaign has been one of the most exciting title chases in Europe’s major leagues, when Napoli moved to within a point of Juve after Koulibaly’s dramatic late headed winner against the leaders.
However, it is advantage Juventus again after Napoli suffered only their third league defeat of the season a day after Juve’s dramatic 3-2 win at Inter Milan.
Koulibaly was sent off after a video assistant referee (VAR) decision for preventing a clear scoring opportunity. Simeone then sprinted clear to set Fiorentina on their way and doubled the lead from close range.
Simeone, 22, completed his hat-trick with a composed finish in almost the last kick of the game.